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Neuroderm
Synapse Repair Serum — NS-01

Synapse Repair Serum

Nine-peptide overnight signal serum

$89.95

30 ml / 1.0 fl oz · Priced in USD

1
  • Free US standard shipping over $75.00 3–5 business days, tracked. Under that, $6.95.
  • 30-day returns, opened or unopened. Full refund policy.
  • A free 5 ml sample ships with every order — add it from Discovery.

One-time purchase — no subscription, no recurring charge. Your statement will show NEURO.

Key actives, at disclosed concentrations

Acetyl Hexapeptide-85%

Best known for the look of expression lines.

Palmitoyl Tripeptide-1 + Tetrapeptide-72%

Supports a firmer-looking surface.

Niacinamide4%

Evens the look of tone and supports a smoother finish.

Concentrations are printed on the carton as well as here. Where an ingredient carries no percentage it is present at a supporting level we do not consider worth claiming.

About this formula

Synapse Repair Serum is the formula Neuroderm was built around. Nine cosmetic peptides — including acetyl hexapeptide-8 at 5% and a palmitoyl tripeptide-1 / tetrapeptide-7 pair at 2% — sit in a thin, fast-absorbing aqueous base with 4% niacinamide and a low-molecular-weight hyaluronic acid blend.

It layers under any moisturizer without pilling and is formulated to be tolerable nightly, including alongside a retinoid on alternating evenings. Fragrance-free, dye-free, non-comedogenic. Net contents 30 ml (1.0 fl oz) in an amber glass bottle with a metered dropper.

How to use

  1. 1Use in the evening on clean, slightly damp skin.
  2. 2Dispense 4–5 drops. Press over face and neck; do not rub in aggressively.
  3. 3Follow with a moisturizer. Allow 60 seconds if layering another active.
  4. 4Nightly. If you also use a retinoid, alternate evenings for the first two weeks.

Full ingredient list

Aqua/Water, Glycerin, Niacinamide, Propanediol, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Tetrapeptide-5, Hexapeptide-11, Pentapeptide-18, Tripeptide-10 Citrulline, Oligopeptide-1, Panthenol, Allantoin, Betaine, Xanthan Gum, Sodium Phytate, Citric Acid, Phenoxyethanol, Ethylhexylglycerin.

Ingredient lists are subject to change. Always read the declaration on the carton you receive. If you have a known allergy, patch test on the inner forearm for 48 hours before facial use. Discontinue use if irritation occurs.

Verified purchases

4.8 out of 5 · 2,417 reviews

I bought Synapse Repair Serum on the strength of the disclosed percentages and it is the first time a product has done exactly what the page said it would.
Helena V.Verified
Took about six weeks before I could see it, which the page did warn me about. Glad I did not give up at four.
Priya S.Verified
Third bottle. The packaging keeps it stable much longer than the clear-bottle version I used before.
Marcus L.Verified

Pairs well with